publications

2026

1. Chromosome-level genome assembly and annotation of the degu (Octodon degus)

   Jeffrey Huey-Chuan Chiu, Nathan R Zemke, Maximiliano Garduno, and 8 more authors

   bioRxiv, 2026
2. Single-Cell Atlas of Transcription and Chromatin States Reveals Regulatory Programs in the Human Brain

   Yang Xie, Lei Chang, Guojie Zhong, and 8 more authors

   bioRxiv, 2026
3. An Integrated Single-Cell and Epigenomic Resource for Comparative Analysis of the Basal Ganglia

   Wenjin Zhang, Wubin Ding , Kai Li, and 8 more authors

   bioRxiv, 2026

2025

1. Droplet Hi-C enables scalable, single-cell profiling of chromatin architecture in heterogeneous tissues

   Lei Chang, Yang Xie, Brett Taylor, and 8 more authors

   Nature Biotechnology, 2025
2. Context-Dependent and Gene-Specific Role of Chromatin Architecture Mediated by Histone Modifiers and Loop-extrusion Machinery

   Melodi Tastemel, Adam Jussila, Bharath Saravanan, and 6 more authors

   bioRxiv, 2025
3. Single cell multiomics and 3D genome architecture reveal novel pathways of human heart failure

   Yang Xie, Luca Tucciarone, Elie N Farah, and 8 more authors

   medRxiv, 2025
4. Single cell multiomics reveals drivers of metabolic dysfunction-associated steatohepatitis

   Weston Elison, Lei Chang, Yang Xie, and 8 more authors

   medRxiv, 2025

2023

1. A comparative atlas of single-cell chromatin accessibility in the human brain

   Yang Eric Li, Sebastian Preissl, Michael Miller, and 8 more authors

   Science, 2023
2. Droplet-based single-cell joint profiling of histone modifications and transcriptomes

   Yang Xie, Chenxu Zhu, Zhaoning Wang, and 4 more authors

   Nature Structural & Molecular Biology, 2023
3. Single-cell analysis of chromatin accessibility in the adult mouse brain

   Songpeng Zu, Yang Eric Li , Kangli Wang, and 8 more authors

   Nature, 2023
4. Conserved and divergent gene regulatory programs of the mammalian neocortex

   Nathan R Zemke, Ethan J Armand , Wenliang Wang, and 8 more authors

   Nature, 2023