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New York Genome Center

Postdoctoral Research Associate

• Led the pilot study for the $100M Center for Multiomic Human Brain Cell Atlas (NIH BRAIN Initiative), establishing feasibility and analytical frameworks for large-scale multimodal profiling.
• Discovered that repressive histone modifications encode epigenetic memory, shaping cell-type-, region-, and species-specific gene regulatory programs across the human brain.
• Authored multiple manuscripts on single-cell integrative analyses of the mammalian brain, focused on active and repressive histone modifications.

University of California San Diego

Postdoctoral Research Associate

• Led data analysis across multi-investigator projects in the NIH 4D Nucleome Program, dissecting gene regulatory mechanisms in heart failure and MASLD/MASH.
• Identified cardiomyocyte-specific erosion of chromatin compartmentalization in human heart failure, and uncovered etiology-specific transcription factors driving progression in cardiomyocytes and fibroblasts.
• Showed that simple steatosis and steatohepatitis are governed by distinct transcriptional programs, and linked major MASH risk loci to putative effector genes.

University of California San Diego

Graduate Student Researcher · Ren Lab

• Developed Droplet Paired-Tag, a high-throughput single-cell multiomic method profiling histone modifications and transcriptomes together; applied it to annotate cell-type-specific chromatin states and regulatory elements in mouse cortex.
• Co-developed Droplet Hi-C and extended it to Paired Hi-C, characterizing structural-variant heterogeneity in cancer models and dynamic ecDNA evolution in glioblastoma under drug resistance.

Salk Institute for Biological Studies

Graduate Student Researcher

• Studied chromosome folding by electron microscopy (ChromEMT) and live-cell imaging.

Graduate Instructional Apprentice - The Cell

Division of Biological Sciences, UC San Diego